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A Novel technique of internal mammary nodal irradiation with intraoperative 192 Ir brachytherapy in breast carcinoma: preliminary experience of a prospective trial.

In International Journal of Radiation Oncology Biology Physics
By: Mahantshetty UM.
Contributor(s): Mittra I | Dinshaw KA | Kinhikar RA | Deshpande D | Shrivastava SK | Jalali R | Badwe RA | Sarin R | .
Material type: materialTypeLabelArticleSeries: Vol 55 Issues 2.Publisher: 2003Description: 540.Subject(s): Prospective trial | India | 192Ir | Brachytherapy | Breast carcinoma | Breast cancer | DDC classification: In: International Journal of Radiation Oncology Biology PhysicsSummary: In carcinoma breast, improved loco-regional control translates in to a better survival. This has led to renewed interest in internal Mammary lymph node chain (IMC) irradiation in high risk patients. Refinement of external beam, techniques to reduce cardiac related mortality for IMC radiation is an area of current radiation research. Even with the advent of techniques such as IMRT, uncertainities regarding the localization of IMC remains. Identification of internal mammary vesels (IMV) is presently considered to be the most suitable method for localization of IMC, as the nodes are ion close proximity to the IMV. Brachytherapy of IMC with intra-operative catheter placement in IMV is a novel approach to reduce the uncertainities of IMC localization. Due to rapid fall off, dose to the critical organs is greatly reduced. The aim of this study was to assess the feasibility of this novel apprach and its impact on reducing the dose to the heart, lung and coronary region. Conclusion: IMC-HDR brachytherapy is a feas
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In carcinoma breast, improved loco-regional control translates in to a better survival. This has led to renewed interest in internal Mammary lymph node chain (IMC) irradiation in high risk patients. Refinement of external beam, techniques to reduce cardiac related mortality for IMC radiation is an area of current radiation research. Even with the advent of techniques such as IMRT, uncertainities regarding the localization of IMC remains. Identification of internal mammary vesels (IMV) is presently considered to be the most suitable method for localization of IMC, as the nodes are ion close proximity to the IMV. Brachytherapy of IMC with intra-operative catheter placement in IMV is a novel approach to reduce the uncertainities of IMC localization. Due to rapid fall off, dose to the critical organs is greatly reduced. The aim of this study was to assess the feasibility of this novel apprach and its impact on reducing the dose to the heart, lung and coronary region.
Conclusion: IMC-HDR brachytherapy is a feas

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